THE INHIBITORY RECEPTORS PD1, TIM3, AND A2AR ARE HIGHLY EXPRESSED DURING MESOCAR T CELL MANUFACTURING IN ADVANCED HUMAN EPITHELIAL OVARIAN CANCER

The inhibitory receptors PD1, Tim3, and A2aR are highly expressed during mesoCAR T cell manufacturing in advanced human epithelial ovarian cancer

Abstract Background Chemotherapy and surgery have been the mainstays of epithelial ovarian cancer (EOC) treatment so far.Cellular immunotherapies such as CAR T cell therapy have recently given hope of a cure for solid tumors like EOC.However, extrinsic factors associated with the CAR T cell manufacturing process and/or intrinsic dysregulation of pa

read more

Imperialist times and its implications for public health

This articles studies the period called by historians as the Big or Bassinet Long x i x century.Besides the x i x century by itself, it encompasses the decades that preceded it and the decades of the First World War.All of them belong to the consolidation of imperialism.From the perspective of public health, the Big x i x Century is important becau

read more